Comparative Bioavailability Study of Two Ramipril Tablet Formulations in Indonesian Healthy Volunteers
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چکیده
منابع مشابه
Comparative Bioavailability Study of Two Ramipril Tablet Formulations in Indonesian Healthy Volunteers
A single-dosed, open-label, randomized two-way crossover design under fasting period with two weeks wash out period was evaluated in 24 subjects. For the analysis of pharmacokinetic properties, the blood samples were drawn taken up to 72 hours after dosing. Plasma concentration of ramipril and ramiprilat were determined using liquid chromatography – tandem mass spectrometry method with TurboIon...
متن کاملComparative Bioavailability of Two Tablet Formulations of Dipyridamole in Healthy Volunteers
The bioavailability of two dipyridamol tablet formulations of (Dipyridamole from Tolidaru and Persantin from Boehringer) was compared in 14 healthy male volunteers who received a single dose of 25 mg of the test (T) and the reference (R) products in a randomized balanced 2-way crossover design. Plasma samples were obtained over a 16 h interval and dipyridamole concentrations determined by HPLC ...
متن کاملComparative Bioavailability of Two Tablet Formulations of Dipyridamole in Healthy Volunteers
The bioavailability of two dipyridamol tablet formulations of (Dipyridamole from Tolidaru and Persantin from Boehringer) was compared in 14 healthy male volunteers who received a single dose of 25 mg of the test (T) and the reference (R) products in a randomized balanced 2-way crossover design. Plasma samples were obtained over a 16 h interval and dipyridamole concentrations determined by HPLC ...
متن کاملComparative bioavailability of two cetirizine tablet formulations in Indonesian healthy volunteers.
AIM To compare the bioavailability of two cetirizine tablet (10 mg) formulations (ZyrtecA from UCB Pharma, Spain as a reference formulation and RyvelA from Novell Pharmaceutical Laboratories, Indonesia as a test formulation). MATERIAL AND METHODS The study was conducted according to an open, randomized, two-period crossover design with a 1-week washout period. Eighteen volunteers participated...
متن کاملcomparative bioavailability of two tablet formulations of dipyridamole in healthy volunteers
the bioavailability of two dipyridamol tablet formulations of (dipyridamole from tolidaru and persantin from boehringer) was compared in 14 healthy male volunteers who received a single dose of 25 mg of the test (t) and the reference (r) products in a randomized balanced 2-way crossover design. plasma samples were obtained over a 16 h interval and dipyridamole concentrations determined by hplc ...
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ژورنال
عنوان ژورنال: Journal of Bioanalysis & Biomedicine
سال: 2009
ISSN: 1948-593X
DOI: 10.4172/1948-593x.1000004